ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2016, Vol. 47 ›› Issue (9): 1940-1946.doi: 10.11843/j.issn.0366-6964.2016.09.024

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Effect of Vanadiumon on the Expression of GABA in the Cerebral Cortex in Broilers

TANG Li,XIN Dan-ning,TIAN Chun-yang,CUI Heng-min*   

  1. (College of Veterinary Medicine,Sichuan Agricultural University,Chengdu 611130,China)
  • Received:2016-04-12 Online:2016-09-23 Published:2016-09-23

Abstract:

To study the effect of vanadium on the chick cerebral cortex γ-aminobutyric acid (GABA) expression,280 1-day-old Avian broilers were chosen and randomly divided into four groups,each group divided into seven sample groups,each sample group have 10 broilers,and fed control diet and diet added vanadium (low dose group:15 mg•kg-1;dose group:30 mg•kg-1;high dose group:45 mg•kg-1) for 6 weeks using the immunohistochemical method to detect the expression of chick cerebral cortex GABA Variety.The results showed that the expression level of the cerebral cortex GABA 42 d chicks,15 mg•kg-1of vanadium-added group was the highest (P<0.01 or P<0.05),followed by 30 mg•kg-1 of vanadium added group (P<0.01 or P<0.05),45 mg•kg-1 of vanadium-added group than the control group (P>0.05);45 mg•kg-1 of vanadium-added group,when at 28 d the cerebral cortex expression levels were significantly (P <0.01) higher than the 14 and 42 d;when at the 14 cortex horizontal cells and astrocytes of GABA expression were higher than 42 d (P>0.05).In summary,it showed that the dietary vanadium and the expression of chick’s cortex GABA exist in a dose and time-effect relationship,suggesting that the regulation of expression may be related to up-regulation of GABA.

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